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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22437 | Tazofelone | LY-213829 | Others |
Tazofelone (LY-213829) is a NSAID used for the treatment of inflammatory bowel disease. | |||
T1752 | NS6180 | Potassium Channel | |
NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation. | |||
T2718 | Palmatine chloride | Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase | |
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties. | |||
T5S0802 | Palmatine | Berbericinine,Burasaine | Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase |
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,... | |||
T4084 | Sibofimloc | VRT-1353385,Antibiotic-202,Antibiotic 202 | Antibacterial , Antibiotic |
Sibofimloc (Antibiotic-202), an antibiotic compound, is used in treating bacterial infections. | |||
T2601 | Vidofludimus | SC12267,4sc-101 | Dehydrogenase , DNA/RNA Synthesis , Interleukin |
Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH). | |||
T17225 | Vercirnon | CCX282-B,GSK-1605786,Traficet-EN | CCR |
Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases. | |||
T64337 | PF-04745637 | PF4745637,PF 4745637,PF 04745637,PF-4745637 | TRP/TRPV Channel |
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1]. | |||
T19379 | Ipsalazide | Autophagy | |
Ipsalazide is a novel salicylazosulfapyridine analog for the treatment of inflammatory bowel disease. | |||
T24997 | ABT-510 acetate | ABT 510 acetate | Apoptosis |
ABT-510 acetate is an endogenous anti-angiogenic TSP peptide inhibitor, a thrombospondin analog, with anti-inflammatory, anti-cancer and anti-angiogenic activity that induces apoptosis and inhibits ovarian tumor growth i... | |||
T28698 | SC-22716 | SC 22716,SC22716 | Aminopeptidase |
SC-22716 is an orally active leukotriene A4 (LTA4) hydrolase inhibitor.SC-22716 has potential anti-inflammatory activity and may be used in the study of inflammatory bowel disease and psoriasis. | |||
T27138 | Declopramide | OXI-104,IMO-B,3-Chloroprocainamide | Apoptosis |
Declopramide (OXI-104) is a novel chemosensitizer with antitumor activity that induces apoptosis and can be used to study colorectal cancer and inflammatory bowel disease. | |||
T2735 | 5-Acetylsalicylic acid | 5-acetyl-2-hydroxybenzoic acid | Others |
5-Acetylsalicylic acid (5-acetyl-2-hydroxybenzoic acid) has anti-inflammatory effects and can be used to treat inflammatory bowel disease, including ulcerative colitis, inflamed anus or rectum, and to maintain remission ... | |||
T20615 | Olsalazine | Dipentium,Salicylic acid | Others |
Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent. | |||
T0646 | 5-Aminosalicylic Acid | Mesalazine,5-ASA,Mesalamine | NF-κB , Lipoxygenase , COX , Glutathione Peroxidase , Endogenous Metabolite , PAK , PPAR |
5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. | |||
T5095 | Oxazolone | 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one | Others |
Oxazolone has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory... | |||
T11179 | Elubrixin | SB-656933 | IL Receptor , CXCR |
Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammat... | |||
T11492 | GSK2983559 free acid | Others , RIP kinase | |
GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammato... | |||
T4319 | Hispidol | (Z)-Hispidol | TNF |
Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 μM. | |||
T79600 | Zharp2-1 | RIP kinase | |
Zharp2-1, a RIPK2 inhibitor, inhibits the transcription of inflammatory cytokines induced by MDP-induced or Listeria monocytogenes infection and alleviates MDP-induced peritonitis symptoms in mice, which can be used for ... |