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Search Results for " inflammatory bowel disease "

20

Compounds

Cat No. Product Name Synonyms Targets
T22437 Tazofelone LY-213829 Others
Tazofelone (LY-213829) is a NSAID used for the treatment of inflammatory bowel disease.
T1752 NS6180 Potassium Channel
NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.
T2718 Palmatine chloride Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
T5S0802 Palmatine Berbericinine,Burasaine Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,...
T4084 Sibofimloc VRT-1353385,Antibiotic-202,Antibiotic 202 Antibacterial , Antibiotic
Sibofimloc (Antibiotic-202), an antibiotic compound, is used in treating bacterial infections.
T2601 Vidofludimus SC12267,4sc-101 Dehydrogenase , DNA/RNA Synthesis , Interleukin
Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).
T17225 Vercirnon CCX282-B,GSK-1605786,Traficet-EN CCR
Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.
T64337 PF-04745637 PF4745637,PF 4745637,PF 04745637,PF-4745637 TRP/TRPV Channel
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].
T19379 Ipsalazide Autophagy
Ipsalazide is a novel salicylazosulfapyridine analog for the treatment of inflammatory bowel disease.
T24997 ABT-510 acetate ABT 510 acetate Apoptosis
ABT-510 acetate is an endogenous anti-angiogenic TSP peptide inhibitor, a thrombospondin analog, with anti-inflammatory, anti-cancer and anti-angiogenic activity that induces apoptosis and inhibits ovarian tumor growth i...
T28698 SC-22716 SC 22716,SC22716 Aminopeptidase
SC-22716 is an orally active leukotriene A4 (LTA4) hydrolase inhibitor.SC-22716 has potential anti-inflammatory activity and may be used in the study of inflammatory bowel disease and psoriasis.
T27138 Declopramide OXI-104,IMO-B,3-Chloroprocainamide Apoptosis
Declopramide (OXI-104) is a novel chemosensitizer with antitumor activity that induces apoptosis and can be used to study colorectal cancer and inflammatory bowel disease.
T2735 5-Acetylsalicylic acid 5-acetyl-2-hydroxybenzoic acid Others
5-Acetylsalicylic acid (5-acetyl-2-hydroxybenzoic acid) has anti-inflammatory effects and can be used to treat inflammatory bowel disease, including ulcerative colitis, inflamed anus or rectum, and to maintain remission ...
T20615 Olsalazine Dipentium,Salicylic acid Others
Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent.
T0646 5-Aminosalicylic Acid Mesalazine,5-ASA,Mesalamine NF-κB , Lipoxygenase , COX , Glutathione Peroxidase , Endogenous Metabolite , PAK , PPAR
5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.
T5095 Oxazolone 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one Others
Oxazolone has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory...
T11179 Elubrixin SB-656933 IL Receptor , CXCR
Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammat...
T11492 GSK2983559 free acid Others , RIP kinase
GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammato...
T4319 Hispidol (Z)-Hispidol TNF
Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 μM.
T79600 Zharp2-1 RIP kinase
Zharp2-1, a RIPK2 inhibitor, inhibits the transcription of inflammatory cytokines induced by MDP-induced or Listeria monocytogenes infection and alleviates MDP-induced peritonitis symptoms in mice, which can be used for ...

Compounds

Tazofelone
T22437
Synonym: LY-213829
Target: Others
NS6180
T1752
Synonym:
Target: Potassium Channel
Palmatine chloride
T2718
Synonym:
Target: Others, Indoleamine 2,3-Dioxygenase (IDO), Aurora Kinase
Palmatine
T5S0802
Synonym: Berbericinine,Burasaine
Target: Indoleamine 2,3-Dioxygenase (IDO), AChR, AChE, Aurora Kinase
Sibofimloc
T4084
Synonym: VRT-1353385,Antibiotic-202,Antibiotic 202
Target: Antibacterial, Antibiotic
Vidofludimus
T2601
Synonym: SC12267,4sc-101
Target: Dehydrogenase, DNA/RNA Synthesis, Interleukin
Vercirnon
T17225
Synonym: CCX282-B,GSK-1605786,Traficet-EN
Target: CCR
PF-04745637
T64337
Synonym: PF4745637,PF 4745637,PF 04745637,PF-4745637
Target: TRP/TRPV Channel
Ipsalazide
T19379
Synonym:
Target: Autophagy
ABT-510 acetate
T24997
Synonym: ABT 510 acetate
Target: Apoptosis
SC-22716
T28698
Synonym: SC 22716,SC22716
Target: Aminopeptidase
Declopramide
T27138
Synonym: OXI-104,IMO-B,3-Chloroprocainamide
Target: Apoptosis
5-Acetylsalicylic acid
T2735
Synonym: 5-acetyl-2-hydroxybenzoic acid
Target: Others
Olsalazine
T20615
Synonym: Dipentium,Salicylic acid
Target: Others
5-Aminosalicylic Acid
T0646
Synonym: Mesalazine,5-ASA,Mesalamine
Target: NF-κB, Lipoxygenase, COX, Glutathione Peroxidase, Endogenous Metabolite, PAK, PPAR
Oxazolone
T5095
Synonym: 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one
Target: Others
Elubrixin
T11179
Synonym: SB-656933
Target: IL Receptor, CXCR
GSK2983559 free acid
T11492
Synonym:
Target: Others, RIP kinase
Hispidol
T4319
Synonym: (Z)-Hispidol
Target: TNF
Zharp2-1
T79600
Synonym:
Target: RIP kinase
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TargetMol